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This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.

Toxicology. --- Biochemistry. --- Animal welfare. --- Pharmacology/Toxicology. --- Biochemistry, general. --- Animal Welfare/Animal Ethics. --- Abuse of animals --- Animal cruelty --- Animals --- Animals, Cruelty to --- Animals, Protection of --- Animals, Treatment of --- Cruelty to animals --- Humane treatment of animals --- Kindness to animals --- Mistreatment of animals --- Neglect of animals --- Prevention of cruelty to animals --- Protection of animals --- Treatment of animals --- Welfare, Animal --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Abuse of --- Social aspects --- Composition --- Toxicology --- Pharmacology. --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect --- Biochemistry --- Animal welfare

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Animal welfare is attracting increasing interest worldwide, but particularly from those in developed countries, who now have the knowledge and resources to be able to offer the best management systems for their farm animals, as well as potentially being able to offer plentiful resources for companion, zoo and laboratory animals. The increased attention given to farm animal welfare in the West derives largely from the fact that the relentless pursuit of financial reward and efficiency has led to the development of intensive animal production systems that challenge the conscience of many consumers in those countries. In developing countries, human survival is still a daily uncertainty, so that provision for animal welfare has to be balanced against human welfare. Welfare is usually provided for only if it supports the output of the animal, be it food, work, clothing, sport or companionship. In re- ity, there are resources for all if they are properly husbanded in both developing and developed countries. The inequitable division of the world’s riches creates physical and psychological poverty for humans and animals alike in many parts of the world. Livestock are the world’s biggest land user (FAO, 2002) and the population is increasing rapidly to meet the need of an expanding human population. Populations of farm animals managed by humans are therefore increasing worldwide, and there is the tendency to allocate fewer resources to each animal.

Cattle. --- Animal welfare. --- Abuse of animals --- Animal cruelty --- Animals --- Animals, Cruelty to --- Animals, Protection of --- Animals, Treatment of --- Cruelty to animals --- Humane treatment of animals --- Kindness to animals --- Mistreatment of animals --- Neglect of animals --- Prevention of cruelty to animals --- Protection of animals --- Treatment of animals --- Welfare, Animal --- Bos taurus --- Bos --- Livestock --- Abuse of --- Social aspects

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It is vital to understand the recent perceptions in animal welfare and its implications in changing global scenarios. The introductory chapter to Animal Welfare provides concise details of the application of emerging these scenarios. The book is self-contained with everything needed to understand the importance of animal welfare and its perspectives. This is the first edition of the book so it covers the introductory level of topics, which are written specifically for veterinary students, classroom use, and practitioners who require more knowledge of animal welfare. The book contains sections on global perspectives, animal health and welfare, and husbandry and welfare. Each section comprises chapters from renowned experts in each area and gives readers a unique opportunity to explore the topic.

Animal welfare. --- Abuse of animals --- Animal cruelty --- Animals --- Animals, Cruelty to --- Animals, Protection of --- Animals, Treatment of --- Cruelty to animals --- Humane treatment of animals --- Kindness to animals --- Mistreatment of animals --- Neglect of animals --- Prevention of cruelty to animals --- Protection of animals --- Treatment of animals --- Welfare, Animal --- Abuse of --- Social aspects --- Life Sciences --- Animal Biology --- Ethology --- Agricultural and Biological Sciences

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While many scholars who write about animals deal with animal agency in some way, this volume is the first to position the question of nonhuman agency as the primary focus of inquiry. Section I presents studies of actual animals demonstrating agency; Section II moves agency into new terrain while considering key representations of animal agency in literature; Section III analyzes animals as mediators and as conveyances of human-to-human communication;and Section IV investigates the agency of beings who defy conventional species categories. The Envoi demonstrates how the microscopic polyp is interwoven into notions of agency and mythical superagency. This volume's interdisciplinary explorations press hard on issues of agency to open up space for more questions about how we can understand relationships between the human and the nonhuman.

Animal welfare. --- Agent (Philosophy) --- Abuse of animals --- Animal cruelty --- Animals --- Animals, Cruelty to --- Animals, Protection of --- Animals, Treatment of --- Cruelty to animals --- Humane treatment of animals --- Kindness to animals --- Mistreatment of animals --- Neglect of animals --- Prevention of cruelty to animals --- Protection of animals --- Treatment of animals --- Welfare, Animal --- Agency (Philosophy) --- Agents --- Person (Philosophy) --- Act (Philosophy) --- Philosophy --- Abuse of --- Social aspects

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Animal welfare. --- Abuse of animals --- Animal cruelty --- Animals --- Animals, Cruelty to --- Animals, Protection of --- Animals, Treatment of --- Cruelty to animals --- Humane treatment of animals --- Kindness to animals --- Mistreatment of animals --- Neglect of animals --- Prevention of cruelty to animals --- Protection of animals --- Treatment of animals --- Welfare, Animal --- Abuse of --- Social aspects